Citicoline Sodium

Category： Chemicals
CAS NO.: 33818-15-4
Appearance: White or off-white crystal powder
Formula: C14H25N4NaO11P2
Molecular Weight: 510.31
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Product name: Citicoline Sodium

Other name: Citicoline sodium Salt, CDP-Choline sodium; cytidine 5'-(trihydrogen diphosphate) p'-(2-(trimethylammonio)ethyl) ester inner salt monosodium salt; sodium5'-O-[({[2-(trimethylammonio)ethoxy]phosphinato}oxy)phosphinato]cytidine

CAS NO.: 33818-15-4

Formula: C14H25N4NaO11P2

Molecular Weight: 510.31

EINECS NO.: 251-689-1

Appearance: White or off-white crystal powder

Solubility: Soluble easily in water, insoluble in ethanol,acetone and chloroform

Product description of Citicoline Sodium:

Citicoline Sodium is composed of ribose, cytosine, phosphoric acid and choline. As an endogenous compound, sodium cytidine choline is an important medium for the synthesis of phospholipids in cell membranes and an external source for the synthesis of acetylcholine, acetylcholine is an important neurotransmitter and plays an important role in nucleotide metabolis.

Citicoline Sodium can improve Hemiplegia caused by stroke can gradually restore the function of the limbs, and can also be used for other functional and conscious disorders caused by acute injury of the central nervous system, as well as for ischemic cerebrovascular disease and vascular dementia.

Specification Sheet of Citicoline Sodium:

ITEM	SPECIFICATION
Appearance	White or off-white crystal powder smell-less.
Identification	1) Chemical reaction 2) The retention time of a major peak meets the requirements. 3) IR: Consistent with the spectrum obtained with reference substance. 4) Show sodium flame
Solubility	Soluble easily in water, insoluble in ethanol,acetone and chloroform
Acid value	Between 6.0-7.5
Clarify and color of solution	Clarifying,colorless
Chlorides	≤0.05%
Ammonium	≤0.05%
Iron	≤0.01%
Phosphate	≤0. 1%
Loss on drying	≤6.0%
5-CMP	≤ 0.3%
The other largest impurities	≤ 0.2%
The other total impurities	≤ 0.7%
Methanol	≤0.3%
Ethanol	≤ 0.5%
Acetone	≤ 0.5%
Heavy metals	≤5ppm
Arsenic	≤0.0001%
Endotoxin	≤0.3EU/mg
Citicoline Sodium (Dry basis)	≥98%
Packing	Pack in paper-drums and two plastic bag inside. Net weight: 25kg/drum
Storage condition	Store in a well closed place with constant low temperature and no direct sun light
Shelf life	Two years when properly stored.

Function of Citicoline Sodium:

Citicoline Sodium can improve the Consciousness disorders after acute craniocerebral trauma and brain surgery can gradually restore the function of limbs in hemiplegia caused by stroke, and can also be used in other central nervous system function and consciousness disorders caused by acute injury, and also used in ischemic cerebrovascular disease and vascular dementia.
1. Brain metabolic activators
2. Boost brain cell respiration
3. Improve circulation
4. Promoting arousal
5. Reducing cerebrovascular resistance

Clinical Applications of Citicoline Sodium:
Brain diseases; neurological disorder; Parkinson's disease; glaucoma.